GZMB Antikörper (AA 21-247)
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- Target Alle GZMB Antikörper anzeigen
- GZMB (Granzyme B (GZMB))
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Bindungsspezifität
- AA 21-247
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GZMB Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Granzyme B protein (21-247AA)
- Isotyp
- IgG
- Top Product
- Discover our top product GZMB Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- GZMB (Granzyme B (GZMB))
- Andere Bezeichnung
- GZMB (GZMB Produkte)
- Synonyme
- CCPI antikoerper, CGL-1 antikoerper, CGL1 antikoerper, CSP-B antikoerper, CSPB antikoerper, CTLA1 antikoerper, CTSGL1 antikoerper, HLP antikoerper, SECT antikoerper, granzyme B antikoerper, GZMB antikoerper
- Hintergrund
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Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Aliases: C11 antibody, Cathepsin G like 1 antibody, Cathepsin G-like 1 antibody, CCPI antibody, CGL 1 antibody, CGL1 antibody, CSP B antibody, CSPB antibody, CTLA 1 antibody, CTLA-1 antibody, CTLA1 antibody, CTSGL1 antibody, Cytotoxic serine protease B antibody, Cytotoxic T lymphocyte associated serine esterase 1 antibody, Cytotoxic T lymphocyte proteinase 2 antibody, Cytotoxic T-lymphocyte proteinase 2 antibody, Fragmentin 2 antibody, Fragmentin-2 antibody, GRAB_HUMAN antibody, Granzyme 2 antibody, Granzyme B (granzyme 2, cytotoxic T lymphocyte associated serine esterase 1) antibody, Granzyme B antibody, Granzyme-2 antibody, GranzymeB antibody, GRB antibody, Gzmb antibody, Hlp antibody, Human lymphocyte protein antibody, Lymphocyte protease antibody, Protease, serine, B antibody, SECT antibody, T cell serine protease 1 3E antibody, T cell serine protease 1-3E antibody, T-cell serine protease 1-3E antibody
- UniProt
- P10144
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose
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