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Paxillin Antikörper (pSer178)

PXN Reaktivität: Human WB, ELISA, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN711221
  • Target Alle Paxillin (PXN) Antikörper anzeigen
    Paxillin (PXN)
    Bindungsspezifität
    • 32
    • 31
    • 21
    • 16
    • 9
    • 9
    • 9
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer178
    Reaktivität
    • 203
    • 109
    • 78
    • 16
    • 9
    • 8
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 195
    • 25
    • 1
    Kaninchen
    Klonalität
    • 185
    • 36
    Polyklonal
    Konjugat
    • 112
    • 10
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Dieser Paxillin Antikörper ist unkonjugiert
    Applikation
    • 157
    • 57
    • 41
    • 40
    • 39
    • 25
    • 23
    • 20
    • 17
    • 14
    • 12
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human Paxillin around the phosphorylation site of Ser178
    Isotyp
    IgG
    Top Product
    Discover our top product PXN Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Stelling-Férez, Gabaldón, Nicolás: "Oleanolic acid stimulation of cell migration involves a biphasic signaling mechanism." in: Scientific reports, Vol. 12, Issue 1, pp. 15065, (2022) (PubMed).

  • Target
    Paxillin (PXN)
    Andere Bezeichnung
    Paxillin (PXN Produkte)
    Synonyme
    AW108311 antikoerper, AW123232 antikoerper, Pax antikoerper, CG18061 antikoerper, CG18576 antikoerper, CG31794 antikoerper, CT40481 antikoerper, CT42454 antikoerper, DPaxillin antikoerper, DPxn antikoerper, DPxn37 antikoerper, Dmel\\CG31794 antikoerper, Dpax antikoerper, DpaxA antikoerper, PDLP antikoerper, dPax antikoerper, pax antikoerper, wu:fw71f12 antikoerper, PXN antikoerper, LOC100220858 antikoerper, paxillin antikoerper, Paxillin antikoerper, paxillin S homeolog antikoerper, paxillin a antikoerper, PXN antikoerper, Pxn antikoerper, Pax antikoerper, pxn.S antikoerper, pxna antikoerper, LOC696336 antikoerper, pxn antikoerper
    Hintergrund

    Synonyms: PXNphospho S178, Paxillin phospho S178, Paxillin phospho Ser178, p-Paxillin Ser178, Paired box protein Pax 1, PAX 1, PAX1, Paxillin alpha, PXN, PXN protein, FLJ16691, FLJ23042, FLJ16691, PAXI_HUMAN, Paxillin, PXN protein.

    Background: Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).

    Gen-ID
    5829
    Pathways
    MAPK Signalweg, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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