GRB14 Antikörper (AA 294-397) (Biotin)

Produktnummer ABIN7154499

Produktdetails anti-GRB14 Antikörper (Biotin)

Target: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Bindungsspezifität: AA 294-397

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRB14 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Growth factor receptor-bound protein 14 protein (294-397AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GRB14

Target: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Andere Bezeichnung: GRB14 (GRB14 Produkte)

Synonyme: GRB14 antikoerper, AI505286 antikoerper, growth factor receptor bound protein 14 antikoerper, GRB14 antikoerper, grb14 antikoerper, Grb14 antikoerper

Hintergrund:

Background: Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.

Aliases: GRB14Growth factor receptor-bound protein 14 antibody, GRB14 adapter protein antibody

UniProt: Q14449