MCF2L Antikörper (AA 850-980)

Produktnummer ABIN7154651

Produktdetails anti-MCF2L Antikörper

Target: MCF2L (MCF.2 Cell Line Derived Transforming Sequence-Like (MCF2L))

Bindungsspezifität: AA 850-980

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCF2L Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Guanine nucleotide exchange factor DBS protein (850-980AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MCF2L

Target: MCF2L (MCF.2 Cell Line Derived Transforming Sequence-Like (MCF2L))

Andere Bezeichnung: MCF2L (MCF2L Produkte)

Hintergrund:

Background: Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (By similarity). Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42 (PubMed:15157669).

Aliases: ARHGEF 14 antibody, DBL''s big sister antibody, DBS antibody, FLJ12122 antibody, Guanine nucleotide exchange factor DBS antibody, KIAA0362 antibody, MCF 2L antibody, MCF.2 cell line derived transforming sequence like antibody, MCF.2 transforming sequence-like antibody, MCF2 like protein antibody, MCF2 transforming sequence like protein antibody, MCF2-transforming sequence-like protein antibody, Mcf2l antibody, MCF2L_HUMAN antibody, OST antibody, OST oncogene antibody

UniProt: O15068

Pathways: Neurotrophin Signalübertragung, Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis