GNAS Antikörper (AA 1-394)
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- Target Alle GNAS Antikörper anzeigen
- GNAS (GNAS Complex Locus (GNAS))
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Bindungsspezifität
- AA 1-394
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GNAS Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Guanine nucleotide-binding protein G(s) subunit alpha isoforms short protein (1-394AA)
- Isotyp
- IgG
- Top Product
- Discover our top product GNAS Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- GNAS (GNAS Complex Locus (GNAS))
- Andere Bezeichnung
- GNAS (GNAS Produkte)
- Hintergrund
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Background: Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs) (PubMed:17110384). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP (PubMed:26206488, PubMed:8702665). GNAS functions downstream of several GPCRs, including beta-adrenergic receptors (PubMed:21488135). Stimulates the Ras signaling pathway via RAPGEF2 (PubMed:12391161).
Aliases: Adenylate cyclase-stimulating G alpha protein antibody, AHO antibody, alternative gene product encoded by XL-exon antibody, C20orf45 antibody, extra large alphas protein antibody, GNAS antibody, GNAS complex locus antibody, GNAS1 antibody, GNAS1 gene, formerly antibody, GNAS1, formerly antibody, GNAS2_HUMAN antibody, GPSA antibody, GSA antibody, GSP antibody, guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 antibody, guanine nucleotide regulatory protein antibody, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short antibody, guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas antibody, NESP antibody, neuroendocrine secretory protein antibody, PHP1A antibody, PHP1B antibody, PHP1C antibody, POH antibody, protein ALEX antibody, secretogranin VI antibody
- UniProt
- P63092
- Pathways
- Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Embryonic Body Morphogenesis
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