GNL3L Antikörper (AA 1-582)

Produktnummer ABIN7154757

Produktdetails anti-GNL3L Antikörper

Target: GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))

Bindungsspezifität: AA 1-582

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNL3L Antikörper ist unkonjugiert

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Guanine nucleotide-binding protein-like 3-like protein (1-582AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GNL3L

Target: GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))

Andere Bezeichnung: GNL3L (GNL3L Produkte)

Synonyme: SI:zK13A21.8 antikoerper, flj10613 antikoerper, flj10613l antikoerper, si:dkey-13a21.8 antikoerper, zgc:110536 antikoerper, BC020354 antikoerper, guanine nucleotide binding protein-like 3 (nucleolar)-like antikoerper, guanine nucleotide binding protein-like 3 (nucleolar)-like S homeolog antikoerper, G protein nucleolar 3 like antikoerper, gnl3l antikoerper, gnl3l.S antikoerper, GNL3L antikoerper, Gnl3l antikoerper

Hintergrund:

Background: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.

Aliases: GNL3LGuanine nucleotide-binding protein-like 3-like protein antibody

UniProt: Q9NVN8