rRNA 2'-O-Methyltransferase Fibrillarin (FBL) (AA 1-64) Antikörper (Biotin)

Produktnummer ABIN7154807

Produktdetails

Target: rRNA 2'-O-Methyltransferase Fibrillarin (FBL)

Bindungsspezifität: AA 1-64

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human H/ACA ribonucleoprotein complex subunit 3 protein (1-64AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: rRNA 2'-O-Methyltransferase Fibrillarin (FBL)

Andere Bezeichnung: NOP1

Hintergrund:

Background: Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (\\\"psi\\\") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

Aliases: DKCB1 antibody, H/ACA ribonucleoprotein complex subunit 3 antibody, homolog of yeast Nop10p antibody, MGC70651 antibody, NOLA3 antibody, NOP10 antibody, NOP10 ribonucleoprotein homolog (yeast) antibody, NOP10_HUMAN antibody, NOP10P antibody, Nucleolar protein 10 antibody, Nucleolar protein family A member 3 antibody, nucleolar protein family A, member 3 (H/ACA small nucleolar RNPs) antibody, snoRNP protein NOP10 antibody

UniProt: Q9NPE3