DKC1 Antikörper (AA 94-170)

Produktnummer ABIN7154810

Produktdetails anti-DKC1 Antikörper

Target: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Bindungsspezifität: AA 94-170

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DKC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human H/ACA ribonucleoprotein complex subunit 4 protein (94-170AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DKC1

Target: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Andere Bezeichnung: DKC1 (DKC1 Produkte)

Hintergrund:

Background: Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (\\\'psi\\\') residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

Aliases: CBF5 antibody, CBF5 homolog antibody, Cbf5p homolog antibody, DKC 1 antibody, DKC antibody, Dkc1 antibody, DKC1_HUMAN antibody, DKCX antibody, Dyskeratosis congenita 1 antibody, Dyskeratosis congenita 1 dyskerin antibody, Dyskerin antibody, H/ACA ribonucleoprotein complex subunit 4 antibody, NAP 57 antibody, NAP57 antibody, NOLA 4 antibody, NOLA4 antibody, Nopp140 associated protein of 57 kDa antibody, Nopp140-associated protein of 57 kDa antibody, Nucleolar protein family A member 4 antibody, Nucleolar protein NAP57 antibody, snoRNP protein DKC1 antibody, XAP 101 antibody, XAP101 antibody

UniProt: O60832

Pathways: Telomere Maintenance