HEY1 Antikörper (AA 200-300)

Produktnummer ABIN7154814

Produktdetails anti-HEY1 Antikörper

Target: HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))

Bindungsspezifität: AA 200-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HEY1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Hairy/enhancer-of-split related with YRPW motif protein 1 protein (200-300AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HEY1

Target: HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))

Andere Bezeichnung: HEY1 (HEY1 Produkte)

Synonyme: BHLHb31 antikoerper, CHF2 antikoerper, HERP2 antikoerper, HESR1 antikoerper, HRT-1 antikoerper, OAF1 antikoerper, AI316788 antikoerper, AI414254 antikoerper, HRT1 antikoerper, Herp2 antikoerper, Hesr1 antikoerper, bHLHb31 antikoerper, hesr-1 antikoerper, id:ibd1292 antikoerper, zgc:110572 antikoerper, bc8 antikoerper, chf2 antikoerper, herp2 antikoerper, hesr1 antikoerper, hrt1 antikoerper, oaf1 antikoerper, xbc8 antikoerper, hes related family bHLH transcription factor with YRPW motif 1 antikoerper, hairy/enhancer-of-split related with YRPW motif 1 antikoerper, hes-related family bHLH transcription factor with YRPW motif 1 antikoerper, hes related family bHLH transcription factor with YRPW motif 1 S homeolog antikoerper, HEY1 antikoerper, Hey1 antikoerper, hey1 antikoerper, hey1.S antikoerper

Hintergrund:

Background: Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (PubMed:11095750). Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3 (PubMed:15485867). Involved in the regulation of liver cancer cells self-renewal (PubMed:25985737).

Aliases: Basic helix loop helix protein OAF1 antibody, bHLHb31 antibody, Cardiovascular helix loop-helix factor 2 antibody, Cardiovascular helix-loop-helix factor 2 antibody, CHF-2 antibody, CHF2 antibody, Class B basic helix-loop-helix protein 31 antibody, Hairy and enhancer of split related protein 1 antibody, Hairy and enhancer of split-related protein 1 antibody, Hairy enhancer-of-split related with YRPW motif protein 1 antibody, Hairy related transcription factor 1 antibody, Hairy-related transcription factor 1 antibody, Hairy/enhancer of split related with YRPW motif 1 antibody, Hairy/enhancer-of-split related with YRPW motif protein 1 antibody, HERP2 antibody, HES related repressor protein 1 antibody, HES-related repressor protein 1 antibody, HES-related repressor protein 2 antibody, HESR-1 antibody, HESR1 antibody, HEY 1 antibody, hey1 antibody, HEY1_HUMAN antibody, hHRT1 antibody, HRT-1 antibody, HRT1 antibody, OAF1 antibody

UniProt: Q9Y5J3

Pathways: Tube Formation