Hsc70 Antikörper (AA 418-597)

Produktnummer ABIN7154885

Produktdetails anti-Hsc70 Antikörper

Target: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Bindungsspezifität: AA 418-597

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Hsc70 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Heat shock cognate 71 kDa protein (418-597AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Hsc70

Target: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Andere Bezeichnung: HSPA8 (HSPA8 Produkte)

Hintergrund:

Background: Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Participates in the ER-associated degradation (ERAD) quality control pathway in conjunction with J domain-containing co-chaperones and the E3 ligase CHIP.

Aliases: 2410008N15Rik antibody, Constitutive heat shock protein 70 antibody, Epididymis luminal protein 33 antibody, Epididymis secretory sperm binding protein Li 72p antibody, Heat shock 70 kDa protein 8 antibody, Heat shock 70kD protein 10 antibody, Heat shock 70kD protein 8 antibody, Heat shock 70 kDa protein 8 antibody, Heat shock cognate 71 kDa protein antibody, Heat shock cognate protein 54 antibody, Heat shock cognate protein 71 kDa antibody, Heat shock protein 8 antibody, Heat shock protein A8 antibody, Heat shock protein family A (Hsp70) member 8 antibody, Heat-shock70-KD protein 10, formerly antibody, HEL 33 antibody, HEL S 72p antibody, HSC54 antibody, HSC71 antibody, Hsc73 antibody, HSP71 antibody, HSP73 antibody, HSP7C_HUMAN antibody, HSPA10 antibody, HSPA8 antibody, LAP1 antibody, Lipopolysaccharide associated protein 1 antibody, LPS associated protein 1 antibody, LPS associated protein antibody, MGC102007 antibody, MGC106514 antibody, MGC114311 antibody, MGC118485 antibody, MGC131511 antibody, MGC29929 antibody, N-myristoyltransferase inhibitor protein 71 antibody, NIP71 antibody

UniProt: P11142