MYSM1 Antikörper (AA 170-311) (HRP)

Produktnummer ABIN7155355

Produktdetails anti-MYSM1 Antikörper (HRP)

Target: MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))

Bindungsspezifität: AA 170-311

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYSM1 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Histone H2A deubiquitinase MYSM1 protein (170-311AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MYSM1

Target: MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))

Andere Bezeichnung: MYSM1 (MYSM1 Produkte)

Synonyme: 2A-DUB antikoerper, 2ADUB antikoerper, RP4-592A1.1 antikoerper, C130067A03Rik antikoerper, C530050H10Rik antikoerper, RGD1311787 antikoerper, 2adub antikoerper, Myb like, SWIRM and MPN domains 1 antikoerper, myb-like, SWIRM and MPN domains 1 antikoerper, Myb like, SWIRM and MPN domains 1 L homeolog antikoerper, MYSM1 antikoerper, Mysm1 antikoerper, mysm1.L antikoerper

Hintergrund:

Background: Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.

Aliases: 2A-DUB antibody, 2ADUB antibody, Histone H2A deubiquitinase antibody, Histone H2A deubiquitinase MYSM1 antibody, KIAA1915 antibody, Myb like SWIRM and MPN domains 1 antibody, Myb like, SWIRM and MPN domain containing protein antibody, Myb like, SWIRM and MPN domains 1 antibody, Myb-like antibody, Myb-like, SWIRM and MPN domains 1 antibody, MYSM 1 antibody, mysm1 antibody, MYSM1 Myb-like, SWIRM and MPN domains 1 antibody, MYSM1_HUMAN antibody, RP4-592A1.1 antibody, SWIRM and MPN domain-containing protein 1 antibody

UniProt: Q5VVJ2

Pathways: Chromatin Binding