H2AFB1 Antikörper (AA 1-115) (HRP)

Produktnummer ABIN7155376

Produktdetails anti-H2AFB1 Antikörper (HRP)

Target: H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))

Bindungsspezifität: AA 1-115

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser H2AFB1 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Histone H2A-Bbd type 1 protein (1-115AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu H2AFB1

Target: H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))

Andere Bezeichnung: H2AFB1 (H2AFB1 Produkte)

Synonyme: H2A.Bbd antikoerper, H2A histone family member B1 antikoerper, H2AFB1 antikoerper

Hintergrund:

Background: Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase. They associate with spliceosome components and are required for mRNA splicing. May participate in spermatogenesis.

Aliases: H2AB1 antibody, H2AFB1 antibody, Histone H2A-Bbd type 1 antibody, H2A Barr body-deficient antibody, H2A.B antibody, H2A.Bbd antibody

UniProt: P0C5Y9

Pathways: Telomere Maintenance