Lysine (K)-Specific Methyltransferase 2B (KMT2B) (AA 145-290) Antikörper

Produktnummer ABIN7155462

Produktdetails

Target: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Bindungsspezifität: AA 145-290

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Histone-lysine N-methyltransferase 2B protein (145-290AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Andere Bezeichnung: KMT2B (KMT2B Produkte)

Synonyme: HRX2 antikoerper, MLL1B antikoerper, MLL2 antikoerper, MLL4 antikoerper, TRX2 antikoerper, WBP7 antikoerper, lysine methyltransferase 2B antikoerper, KMT2B antikoerper

Hintergrund:

Background: Histone methyltransferase. Methylates \'Lys-4\' of histone H3. H3 \'Lys-4\' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.

Aliases: Histone-lysine N-methyltransferase 2B antibody, HRX2 antibody, KIAA0304 gene product antibody, KMT2B antibody, KMT2B_HUMAN antibody, Likely ortholog of mouse WW domain binding protein 7 antibody, Lysine N-methyltransferase 2B antibody, mixed lineage leukemia 4 antibody, Mixed lineage leukemia gene homolog 2 protein antibody, MLL2 antibody, myeloid lymphoid leukemia 4 antibody, Myeloid lymphoid or mixed lineage leukemia protein 4 antibody, Myeloid/lymphoid or mixed-lineage leukemia protein 4 antibody, Trithorax homolog 2 antibody, trithorax homologue 2 antibody, TRX2 antibody, WBP-7 antibody, WBP7 antibody, WW domain-binding protein 7 antibody

UniProt: Q9UMN6

Pathways: Warburg Effekt