EZH1 Antikörper (AA 160-280)
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- Target Alle EZH1 Antikörper anzeigen
- EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
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Bindungsspezifität
- AA 160-280
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EZH1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Histone-lysine N-methyltransferase EZH1 protein (160-280AA)
- Isotyp
- IgG
- Top Product
- Discover our top product EZH1 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
- Andere Bezeichnung
- EZH1 (EZH1 Produkte)
- Synonyme
- KMT6B antikoerper, si:ch211-250i3.1 antikoerper, zgc:136829 antikoerper, AW557915 antikoerper, mKIAA0388 antikoerper, EZH1 antikoerper, enhancer of zeste 1 polycomb repressive complex 2 subunit antikoerper, EZH1 antikoerper, ezh1 antikoerper, Ezh1 antikoerper
- Hintergrund
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Background: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates \\\'Lys-27\\\' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate \\\'Lys-27\\\' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Aliases: Enhancer of zeste homolog 1 (Drosophila) antibody, Enhancer of zeste homolog 1 antibody, ENX-2 antibody, ENX2 antibody, Ezh1 antibody, EZH1_HUMAN antibody, Histone-lysine N-methyltransferase EZH1 antibody
- UniProt
- Q92800
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