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EZH1 Antikörper (AA 160-280)

EZH1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7155474
  • Target Alle EZH1 Antikörper anzeigen
    EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 160-280
    Reaktivität
    • 63
    • 38
    • 29
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 60
    • 3
    • 1
    Kaninchen
    Klonalität
    • 61
    • 3
    Polyklonal
    Konjugat
    • 33
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EZH1 Antikörper ist unkonjugiert
    Applikation
    • 50
    • 28
    • 22
    • 13
    • 13
    • 11
    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Histone-lysine N-methyltransferase EZH1 protein (160-280AA)
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
    Andere Bezeichnung
    EZH1 (EZH1 Produkte)
    Synonyme
    KMT6B antikoerper, si:ch211-250i3.1 antikoerper, zgc:136829 antikoerper, AW557915 antikoerper, mKIAA0388 antikoerper, EZH1 antikoerper, enhancer of zeste 1 polycomb repressive complex 2 subunit antikoerper, EZH1 antikoerper, ezh1 antikoerper, Ezh1 antikoerper
    Hintergrund

    Background: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates \\\'Lys-27\\\' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate \\\'Lys-27\\\' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

    Aliases: Enhancer of zeste homolog 1 (Drosophila) antibody, Enhancer of zeste homolog 1 antibody, ENX-2 antibody, ENX2 antibody, Ezh1 antibody, EZH1_HUMAN antibody, Histone-lysine N-methyltransferase EZH1 antibody

    UniProt
    Q92800
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