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MEOX1 Antikörper (AA 1-254)

MEOX1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7155798
  • Target Alle MEOX1 Antikörper anzeigen
    MEOX1 (Mesenchyme Homeobox 1 (MEOX1))
    Bindungsspezifität
    • 8
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-254
    Reaktivität
    • 47
    • 15
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 38
    • 9
    Kaninchen
    Klonalität
    • 39
    • 8
    Polyklonal
    Konjugat
    • 30
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MEOX1 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 24
    • 13
    • 7
    • 4
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Homeobox protein MOX-1 protein (1-254AA)
    Isotyp
    IgG
    Top Product
    Discover our top product MEOX1 Primärantikörper
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MEOX1 (Mesenchyme Homeobox 1 (MEOX1))
    Andere Bezeichnung
    MEOX1 (MEOX1 Produkte)
    Hintergrund

    Background: Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome.

    Aliases: Homeobox protein MOX-1 antibody, MEOX1 antibody, MEOX1_HUMAN antibody, Mesenchyme homeo box 1 antibody, Mesenchyme homeobox 1 antibody, MOX 1 antibody, MOX1 antibody

    UniProt
    P50221
    Pathways
    Chromatin Binding
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