HOMER1 Antikörper (AA 1-354)

Produktnummer ABIN7155877

Produktdetails anti-HOMER1 Antikörper

Target: HOMER1 (Homer Homolog 1 (HOMER1))

Bindungsspezifität: AA 1-354

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOMER1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Homer protein homolog 1 protein (1-354AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HOMER1

Target: HOMER1 (Homer Homolog 1 (HOMER1))

Andere Bezeichnung: HOMER1 (HOMER1 Produkte)

Synonyme: HOMER antikoerper, HOMER1A antikoerper, HOMER1B antikoerper, HOMER1C antikoerper, SYN47 antikoerper, Ves-1 antikoerper, HOMER1 antikoerper, PSD-Zip45 antikoerper, homer1 antikoerper, zgc:100854 antikoerper, zgc:92844 antikoerper, HOMER1F antikoerper, Vesl-1 antikoerper, homer antikoerper, xhomer1 antikoerper, BEST:LD03829 antikoerper, CG11324 antikoerper, Dhom antikoerper, Dhomer antikoerper, Dm Homer antikoerper, Dmel\CG11324 antikoerper, Dvh antikoerper, Hom antikoerper, Homer antikoerper, LD03829 antikoerper, dhom antikoerper, homer scaffolding protein 1 antikoerper, homer scaffolding protein 1b antikoerper, homer scaffolding protein 1 L homeolog antikoerper, CG11324 gene product from transcript CG11324-RD antikoerper, HOMER1 antikoerper, Homer1 antikoerper, homer1b antikoerper, homer1.L antikoerper, homer antikoerper

Hintergrund:

Background: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development. Forms a high-order complex with SHANK1, which in turn is necessary for the structural and functional integrity of dendritic spines (By similarity).

Aliases: HOME1_HUMAN antibody, Homer antibody, HOMER 1A antibody, HOMER 1B antibody, HOMER 1C antibody, Homer homolog 1 (Drosophila) antibody, homer homolog 1 antibody, Homer protein homolog 1 antibody, homer scaffolding protein 1 antibody, Homer, Drosophila, homolog of, 1 antibody, Homer, neuronal immediate early gene, 1 antibody, Homer-1 antibody, Homer1 antibody, HOMER1A antibody, HOMER1B antibody, HOMER1C antibody, SYN47 antibody, Ves 1 antibody

UniProt: Q86YM7

Pathways: Skeletal Muscle Fiber Development