HORMAD2 Antikörper (AA 14-307)

Produktnummer ABIN7155901

Produktdetails anti-HORMAD2 Antikörper

Target: HORMAD2 (HORMA Domain Containing 2 (HORMAD2))

Bindungsspezifität: AA 14-307

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HORMAD2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human HORMA domain-containing protein 2 protein (14-307AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HORMAD2

Target: HORMAD2 (HORMA Domain Containing 2 (HORMAD2))

Andere Bezeichnung: HORMAD2 (HORMAD2 Produkte)

Synonyme: 4930529M09Rik antikoerper, HORMA domain containing 2 antikoerper, HORMAD2 antikoerper, Hormad2 antikoerper

Hintergrund:

Background: Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation.

Aliases: 4930529M09Rik antibody, CT46.2 antibody, HORM2_HUMAN antibody, HORMA domain containing 2 antibody, HORMA domain-containing protein 2 antibody, Hormad2 antibody, MGC26710 antibody, RP23-329P17.4 antibody

UniProt: Q8N7B1