IGKC Antikörper (AA 1-107)

Produktnummer ABIN7156094

Produktdetails anti-IGKC Antikörper

Target: IGKC (Immunoglobulin kappa Constant (IGKC))

Bindungsspezifität: AA 1-107

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGKC Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Immunoglobulin kappa constant protein (1-107AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IGKC

Target: IGKC (Immunoglobulin kappa Constant (IGKC))

Andere Bezeichnung: IGKC (IGKC Produkte)

Synonyme: HCAK1 antikoerper, IGKCD antikoerper, Km antikoerper, IGKC antikoerper, Igk-C antikoerper, immunoglobulin kappa constant antikoerper, immunoglobulin kappa constant L homeolog antikoerper, IGKC antikoerper, LOC708048 antikoerper, igkc antikoerper, igkc.L antikoerper, Igkc antikoerper

Hintergrund:

Background: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).

Aliases: IGKCImmunoglobulin kappa constant antibody, Ig kappa chain C region antibody, Ig kappa chain C region AG antibody, Ig kappa chain C region CUM antibody, Ig kappa chain C region EU antibody, Ig kappa chain C region OU antibody, Ig kappa chain C region ROY antibody, Ig kappa chain C region TI antibody

UniProt: P01834