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KPNA4 Antikörper (AA 51-239) (FITC)

KPNA4 Reaktivität: Human Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN7156124
  • Target Alle KPNA4 Antikörper anzeigen
    KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-239
    Reaktivität
    • 42
    • 36
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Human
    Wirt
    • 50
    • 1
    • 1
    Kaninchen
    Klonalität
    • 51
    • 1
    Polyklonal
    Konjugat
    • 23
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KPNA4 Antikörper ist konjugiert mit FITC
    Applikation
    Bitte anfragen
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Importin subunit alpha-3 protein (51-239AA)
    Isotyp
    IgG
    Top Product
    Discover our top product KPNA4 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))
    Andere Bezeichnung
    KPNA4 (KPNA4 Produkte)
    Synonyme
    IPOA3 antikoerper, QIP1 antikoerper, SRP3 antikoerper, 6 antikoerper, ATIMPALPHA3 antikoerper, IMPA-3 antikoerper, IMPORTIN ALPHA 3 antikoerper, IMPORTIN ALPHA ISOFORM 3 antikoerper, MODIFIER OF SNC1 antikoerper, T10M13.16 antikoerper, T10M13_16 antikoerper, LOC100224013 antikoerper, 1110058D08Rik antikoerper, importin antikoerper, ipoa3 antikoerper, qip1 antikoerper, srp3 antikoerper, impa3 antikoerper, wu:fa56d07 antikoerper, wu:fa66g10 antikoerper, wu:fe14c04 antikoerper, wu:fi04h11 antikoerper, wu:fi19b05 antikoerper, karyopherin subunit alpha 4 antikoerper, ARM repeat superfamily protein antikoerper, importin alpha 3 antikoerper, karyopherin (importin) alpha 4 antikoerper, karyopherin alpha 4 (importin alpha 3) S homeolog antikoerper, karyopherin alpha 4 (importin alpha 3) antikoerper, KPNA4 antikoerper, MOS6 antikoerper, LOC100533341 antikoerper, Kpna4 antikoerper, kpna4.S antikoerper, kpna4 antikoerper
    Hintergrund

    Background: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.

    Aliases: FLJ31113 antibody, IMA3_HUMAN antibody, Importin alpha 3 antibody, Importin alpha 4 subunit antibody, Importin alpha Q1 antibody, Importin subunit alpha 3 antibody, Importin subunit alpha-3 antibody, IPO A3 antibody, IPOA 3 antibody, IPOA3 antibody, Karyopherin alpha 4 (importin alpha 3) antibody, Karyopherin alpha 4 antibody, Karyopherin alpha 4 importin alpha 3 antibody, Karyopherin alpha 4 subunit antibody, Karyopherin subunit alpha 4 antibody, Karyopherin subunit alpha-4 antibody, KPNA 4 antibody, Kpna4 antibody, MGC12217 antibody, MGC26703 antibody, OTTHUMP00000213880 antibody, QIP 1 antibody, Qip1 antibody, Qip1 protein antibody, SRP 3 antibody, SRP3 antibody

    UniProt
    O00629
    Pathways
    Protein targeting to Nucleus
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