ING3 Antikörper (AA 51-223)
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- Target Alle ING3 Antikörper anzeigen
- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
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Bindungsspezifität
- AA 51-223
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ING3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Inhibitor of growth protein 3 protein (51-223AA)
- Isotyp
- IgG
- Top Product
- Discover our top product ING3 Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:2000-1:10000, IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
- Andere Bezeichnung
- ING3 (ING3 Produkte)
- Hintergrund
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Background: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
Aliases: ING3 antibody, HSPC301 antibody, Inhibitor of growth protein 3 antibody, p47ING3 antibody
- UniProt
- Q9NXR8
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