ING4 Antikörper (AA 75-249)

Produktnummer ABIN7156253

Produktdetails anti-ING4 Antikörper

Target: ING4 (Inhibitor of Growth Family, Member 4 (ING4))

Bindungsspezifität: AA 75-249

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ING4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Inhibitor of growth protein 4 protein (75-249AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ING4

Target: ING4 (Inhibitor of Growth Family, Member 4 (ING4))

Andere Bezeichnung: ING4 (ING4 Produkte)

Synonyme: wu:fb11d09 antikoerper, wu:fb50e02 antikoerper, zgc:110619 antikoerper, ING4 antikoerper, my036 antikoerper, p29ING4 antikoerper, D6Wsu147e antikoerper, D6Xrf92 antikoerper, inhibitor of growth family, member 4 antikoerper, inhibitor of growth family member 4 antikoerper, ing4 antikoerper, ING4 antikoerper, Ing4 antikoerper

Hintergrund:

Background: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor\'s (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). Can enhance aopotosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity).

Aliases: Brain my036 protein antibody, Candidate tumor suppressor p33 ING 1 homolog antibody, Candidate tumor suppressor p33 ING1 homolog antibody, D6Wsu147e antibody, D6Xrf92 antibody, ING 1 like protein antibody, ING 4 antibody, ING1 like protein antibody, ING4 antibody, ING4_HUMAN antibody, Inhibitor of growth family member 4 antibody, Inhibitor of growth family member 4 long isoform antibody, Inhibitor of growth protein 4 antibody, MGC12557 antibody, my036 antibody, p29 ING 4 antibody, p29 ING4 antibody, p29ING4 antibody

UniProt: Q9UNL4