Plexin B2 Antikörper (AA 1458-1673) (Biotin)

Produktnummer ABIN7156268

Produktdetails anti-Plexin B2 Antikörper (Biotin)

Target: Plexin B2 (PLXNB2)

Bindungsspezifität: AA 1458-1673

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Plexin B2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Antigen Affinity purified & Affinity purified

Immunogen: Recombinant Human Inhibitor of nuclear factor kappa-B kinase-interacting protein (1458-1673AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Plexin B2

Target: Plexin B2 (PLXNB2)

Andere Bezeichnung: PLXNB2 (PLXNB2 Produkte)

Hintergrund:

Background: Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at \'Tyr-1248\'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42. Down-regulates macrophage migration in wound-healing assays (in vitro) (By similarity).

Aliases: PLXNB2 antibody, KIAA0315 antibody, Plexin-B2 antibody, MM1 antibody

UniProt: O15031

Pathways: Tube Formation