ITPK1 Antikörper (AA 185-414)

Produktnummer ABIN7156320

Produktdetails anti-ITPK1 Antikörper

Target: ITPK1 (Inositol-Tetrakisphosphate 1-Kinase (ITPK1))

Bindungsspezifität: AA 185-414

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITPK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Inositol-tetrakisphosphate 1-kinase protein (185-414AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ITPK1

Target: ITPK1 (Inositol-Tetrakisphosphate 1-Kinase (ITPK1))

Andere Bezeichnung: ITPK1 (ITPK1 Produkte)

Synonyme: ITRPK1 antikoerper, BC031182 antikoerper, wu:fj15d08 antikoerper, zgc:56075 antikoerper, inositol-tetrakisphosphate 1-kinase antikoerper, inositol 1,3,4-triphosphate 5/6 kinase antikoerper, inositol-tetrakisphosphate 1-kinase L homeolog antikoerper, inositol-tetrakisphosphate 1-kinase a antikoerper, ITPK1 antikoerper, Itpk1 antikoerper, itpk1.L antikoerper, itpk1a antikoerper

Hintergrund:

Background: Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain.

Aliases: 3 antibody, 4)P(3) 5/6-kinase antibody, 4-trisphosphate 5/6-kinase antibody, Inositol 1 3 4 triphosphate 5/6 kinase antibody, Inositol 1 3 4 trisphosphate 5/6 kinase antibody, Inositol 1 antibody, Inositol tetrakisphosphate 1 kinase antibody, Inositol triphosphate 5/6 kinase antibody, Inositol-tetrakisphosphate 1-kinase antibody, Inositol-triphosphate 5/6-kinase antibody, Ins(1 3 4)P(3) 5/6 kinase antibody, Ins(1 antibody, ITPK 1 antibody, itpk1 antibody, ITPK1_HUMAN antibody, ITRPK 1 antibody, ITRPK1 antibody

UniProt: Q13572