INTS6 Antikörper (AA 571-795)

Produktnummer ABIN7156417

Produktdetails anti-INTS6 Antikörper

Target: INTS6 (Integrator Complex Subunit 6 (INTS6))

Bindungsspezifität: AA 571-795

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INTS6 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Integrator complex subunit 6 protein (571-795AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu INTS6

Target: INTS6 (Integrator Complex Subunit 6 (INTS6))

Andere Bezeichnung: INTS6 (INTS6 Produkte)

Hintergrund:

Background: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3\\\'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). May have a tumor suppressor role, an ectopic expression suppressing tumor cell growth (PubMed:15254679, PubMed:16239144).

Aliases: DBI 1 antibody, DBI-1 antibody, DBI1 antibody, DDX26 antibody, DDX26A antibody, DEAD box protein antibody, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 26 antibody, Deleted in cancer 1 antibody, DICE1 antibody, DKFZp434B105 antibody, HDB antibody, Int6 antibody, INT6_HUMAN antibody, Integrator complex subunit 6 antibody, INTS 6 antibody, ints6 antibody, Notchl2 antibody, OTTHUMP00000018439 antibody, OTTHUMP00000215034 antibody, OTTHUMP00000215036 antibody, Protein DDX26 antibody, Protein deleted in cancer 1 antibody, RNA helicase HDB antibody

UniProt: Q9UL03