ITGA7 Antikörper (AA 175-283)

Produktnummer ABIN7156450

Produktdetails anti-ITGA7 Antikörper

Target: ITGA7 (Integrin, alpha 7 (ITGA7))

Bindungsspezifität: AA 175-283

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGA7 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Integrin alpha-7 protein (175-283AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ITGA7

Target: ITGA7 (Integrin, alpha 7 (ITGA7))

Andere Bezeichnung: ITGA7 (ITGA7 Produkte)

Synonyme: [a]7 antikoerper, alpha7 antikoerper, integrin alpha 7 antikoerper, integrin subunit alpha 7 antikoerper, Itga7 antikoerper, ITGA7 antikoerper

Hintergrund:

Background: Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.

Aliases: alpha 7 antibody, FLJ25220 antibody, Integrin alpha 7 antibody, Integrin alpha 7 chain antibody, Integrin alpha 7 heavy chain antibody, Integrin alpha 7 light chain antibody, Integrin alpha-7 70 kDa form antibody, ITA7_HUMAN antibody, ITGA 7 antibody, Itga7 antibody

UniProt: Q13683

Pathways: Integrin Complex