IL29 Antikörper (AA 20-200)

Produktnummer ABIN7156607

Produktdetails anti-IL29 Antikörper

Target: IL29 (Interleukin 29 (IL29))

Bindungsspezifität: AA 20-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL29 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Interferon lambda-1 protein (20-200AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IL29

Target: IL29 (Interleukin 29 (IL29))

Andere Bezeichnung: IFNL1 (IL29 Produkte)

Synonyme: IL-29 antikoerper, IL29 antikoerper, interferon lambda 1 antikoerper, interferon lambda-1 antikoerper, interleukin 29 (interferon, lambda 1) antikoerper, IFNL1 antikoerper, LOC612539 antikoerper, IL29 antikoerper

Hintergrund:

Background: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

Aliases: IFNL1 antibody, IL29 antibody, ZCYTO21Interferon lambda-1 antibody, IFN-lambda-1 antibody, Cytokine Zcyto21 antibody, Interleukin-29 antibody, IL-29 antibody

UniProt: Q8IU54