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IL28B Antikörper (AA 22-196)

IL28B Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7156612
  • Target Alle IL28B Antikörper anzeigen
    IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-196
    Reaktivität
    • 33
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 30
    • 4
    • 1
    Kaninchen
    Klonalität
    • 30
    • 5
    Polyklonal
    Konjugat
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL28B Antikörper ist unkonjugiert
    Applikation
    • 26
    • 16
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Interferon lambda-3 protein (22-196AA)
    Isotyp
    IgG
    Top Product
    Discover our top product IL28B Primärantikörper
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))
    Andere Bezeichnung
    IFNL3 (IL28B Produkte)
    Synonyme
    Il28b antikoerper, IFL-1 antikoerper, IL-28B antikoerper, INF-alpha antikoerper, INF-lambda antikoerper, Il28 antikoerper, IL28B antikoerper, IL28C antikoerper, interferon, lambda 3 antikoerper, interferon lambda 3 antikoerper, Ifnl3 antikoerper, IFNL3 antikoerper
    Hintergrund

    Background: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

    Aliases: Cytokine ZCYTO22 antibody, IFN-lambda-3 antibody, IFN-lambda-4 antibody, IL-28B antibody, IL-28C antibody, IL28B antibody, IL28B_HUMAN antibody, IL28C antibody, Interferon lambda-3 antibody, Interferon lambda-4 antibody, interleukin 28B (interferon, lambda 3) antibody, Interleukin 28C antibody, Interleukin-28B antibody, Interleukin-28C antibody

    UniProt
    Q8IZI9
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