IRF8 Antikörper (AA 137-426)

Produktnummer ABIN7156635

Produktdetails anti-IRF8 Antikörper

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Bindungsspezifität: AA 137-426

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF8 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Interferon regulatory factor 8 protein (137-426AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IRF8

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Andere Bezeichnung: IRF8 (IRF8 Produkte)

Synonyme: zgc:92252 antikoerper, IRF8 antikoerper, MGC140338 antikoerper, DKFZp469B0320 antikoerper, H-ICSBP antikoerper, ICSBP antikoerper, ICSBP1 antikoerper, IRF-8 antikoerper, icsbp1 antikoerper, AI893568 antikoerper, Icsbp1 antikoerper, Myls antikoerper, interferon regulatory factor 8 antikoerper, interferon regulatory factor 8 L homeolog antikoerper, irf8 antikoerper, IRF8 antikoerper, irf8.L antikoerper, Irf8 antikoerper

Hintergrund:

Background: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5\\\'-TGAnTCA/GAAA-3\\\'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes.

Aliases: H ICSBP antibody, H-ICSBP antibody, HGNC:5358 antibody, HICSBP antibody, ICSBP 1 antibody, ICSBP antibody, ICSBP1 antibody, Interferon consensus sequence binding protein 1 antibody, Interferon consensus sequence binding protein antibody, Interferon consensus sequence-binding protein antibody, Interferon regulatory factor 8 antibody, IRF 8 antibody, IRF-8 antibody, Irf8 antibody, IRF8_HUMAN antibody, MYLS antibody

UniProt: Q02556

Pathways: Cellular Response to Molecule of Bacterial Origin