IRF9 Antikörper (AA 44-180)

Produktnummer ABIN7156637

Produktdetails anti-IRF9 Antikörper

Target: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Bindungsspezifität: AA 44-180

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Interferon regulatory factor 9 protein (44-180AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IRF9

Target: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Andere Bezeichnung: IRF9 (IRF9 Produkte)

Synonyme: IRF-9 antikoerper, ISGF3 antikoerper, ISGF3G antikoerper, p48 antikoerper, zgc:92097 antikoerper, Irf-9 antikoerper, Isgf3g antikoerper, interferon regulatory factor 9 antikoerper, IRF9 antikoerper, irf9 antikoerper, Irf9 antikoerper

Hintergrund:

Background: Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Aliases: IFN alpha responsive transcription factor subunit antibody, IFN-alpha-responsive transcription factor subunit antibody, Interferon regulatory factor 9 antibody, interferon stimulated transcription factor 3 antibody, Interferon-stimulated gene factor 3 gamma antibody, interferon-stimulated transcription factor 3, gamma 48 kDa antibody, IRF 9 antibody, IRF-9 antibody, Irf9 antibody, IRF9_HUMAN antibody, ISGF 3 gamma antibody, ISGF-3 gamma antibody, ISGF3 antibody, ISGF3 p48 subunit antibody, ISGF3G antibody, OTTHUMP00000164692 antibody, OTTHUMP00000164693 antibody, p48 antibody, Transcriptional regulator ISGF3 subunit gamma antibody

UniProt: Q00978

Pathways: JAK-STAT Signalweg, Interferon-gamma Pathway, Hepatitis C