Inversin Antikörper (AA 1-101) (HRP)

Produktnummer ABIN7157011

Produktdetails anti-Inversin Antikörper (HRP)

Target: Inversin (INVS)

Bindungsspezifität: AA 1-101

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Inversin Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Inversin protein (1-101AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Inversin

Target: Inversin (INVS)

Andere Bezeichnung: INVS (INVS Produkte)

Synonyme: invs-a antikoerper, INVS antikoerper, MGC140477 antikoerper, inv antikoerper, NPH2 antikoerper, NPHP2 antikoerper, INV antikoerper, Nphp2 antikoerper, RGD1563359 antikoerper, wu:fe47e11 antikoerper, inversin S homeolog antikoerper, inversin antikoerper, Inversin antikoerper, invs.S antikoerper, INVS antikoerper, Bm1_38710 antikoerper, PTRG_09181 antikoerper, EAMY_RS33690 antikoerper, LOAG_11716 antikoerper, invs antikoerper, Invs antikoerper

Hintergrund:

Background: Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity).

Aliases: INVS antibody, INV antibody, NPHP2 antibody, Inversin antibody, Inversion of embryo turning homolog antibody, Nephrocystin-2 antibody

UniProt: Q9Y283