Kallikrein 14 Antikörper (AA 114-225)

Produktnummer ABIN7157204

Produktdetails anti-Kallikrein 14 Antikörper

Target: Kallikrein 14 (KLK14)

Bindungsspezifität: AA 114-225

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 14 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Kallikrein-14 protein (114-225AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Kallikrein 14

Target: Kallikrein 14 (KLK14)

Andere Bezeichnung: KLK14 (KLK14 Produkte)

Synonyme: GK14 antikoerper, KLK-L6 antikoerper, kallikrein related-peptidase 14 antikoerper, kallikrein related peptidase 14 antikoerper, Klk14 antikoerper, KLK14 antikoerper

Hintergrund:

Background: Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3. May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface. May be involved in several aspects of tumor progression including growth, invasion and angiogenesis.

Aliases: hK14 antibody, Kallikrein 14 antibody, Kallikrein like protein 6 antibody, Kallikrein-14 antibody, Kallikrein-like protein 6 antibody, KLK L6 antibody, KLK-L6 antibody, KLK14 antibody, KLK14_HUMAN antibody

UniProt: Q9P0G3

Pathways: Komplementsystem, Regulation of G-Protein Coupled Receptor Protein Signaling