Kallikrein 6 Antikörper (AA 22-244)

Produktnummer ABIN7157217

Produktdetails anti-Kallikrein 6 Antikörper

Target: Kallikrein 6 (KLK6)

Bindungsspezifität: AA 22-244

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Kallikrein-6 protein (22-244AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Kallikrein 6

Target: Kallikrein 6 (KLK6)

Andere Bezeichnung: KLK6 (KLK6 Produkte)

Synonyme: Bssp antikoerper, Klk7 antikoerper, PRSS18 antikoerper, PRSS9 antikoerper, SP59 antikoerper, hK6 antikoerper, Prss9 antikoerper, AI849898 antikoerper, BSP antikoerper, Klk29 antikoerper, MSP antikoerper, Prss18 antikoerper, neurosin antikoerper, kallikrein related peptidase 6 antikoerper, kallikrein related-peptidase 6 antikoerper, kallikrein-6 antikoerper, KLK6 antikoerper, Klk6 antikoerper, LOC100716801 antikoerper

Hintergrund:

Background: Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis.

Aliases: Bssp antibody, hK 6 antibody, hK6 antibody, Kallikrein 6 precursor antibody, Kallikrein related peptidase 6 antibody, Kallikrein-6 antibody, Kallikrein6 antibody, KLK 6 antibody, Klk 7 antibody, KLK 9 antibody, Klk29 antibody, Klk6 antibody, KLK6_HUMAN antibody, Klk7 antibody, KLK9 antibody, MGC9355 antibody, mGK 1 antibody, mGK1 antibody, MSP antibody, Neurosin antibody, Protease M antibody, Protease serine 18 antibody, Protease serine 9 antibody, PRSS 18 antibody, PRSS 9 antibody, PRSS18 antibody, PRSS9 antibody, Serine protease 18 antibody, Serine protease 9 antibody, SP 59 antibody, SP59 antibody, Tissue kallikrein antibody, TK antibody, Zyme antibody

UniProt: Q92876

Pathways: Komplementsystem, Regulation of G-Protein Coupled Receptor Protein Signaling