KLHL22 Antikörper (AA 2-300) (HRP)
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- Target Alle KLHL22 Antikörper anzeigen
- KLHL22 (Kelch-Like 22 (KLHL22))
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Bindungsspezifität
- AA 2-300
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KLHL22 Antikörper ist konjugiert mit HRP
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Applikation
- ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Kelch-like protein 22 protein (2-300AA)
- Isotyp
- IgG
- Top Product
- Discover our top product KLHL22 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- KLHL22 (Kelch-Like 22 (KLHL22))
- Andere Bezeichnung
- KLHL22 (KLHL22 Produkte)
- Hintergrund
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Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.
Aliases: KLHL22Kelch-like protein 22 antibody
- UniProt
- Q53GT1
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