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KIF14 Antikörper (AA 261-531)

KIF14 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7157595
  • Target Alle KIF14 Antikörper anzeigen
    KIF14 (Kinesin Family Member 14 (KIF14))
    Bindungsspezifität
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 261-531
    Reaktivität
    • 23
    • 4
    • 4
    • 1
    Human
    Wirt
    • 22
    • 1
    Kaninchen
    Klonalität
    • 23
    Polyklonal
    Konjugat
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KIF14 Antikörper ist unkonjugiert
    Applikation
    • 12
    • 9
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Kinesin-like protein KIF14 protein (261-531AA)
    Isotyp
    IgG
    Top Product
    Discover our top product KIF14 Primärantikörper
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    KIF14 (Kinesin Family Member 14 (KIF14))
    Andere Bezeichnung
    KIF14 (KIF14 Produkte)
    Synonyme
    wu:fi16h07 antikoerper, si:dkey-39e8.3 antikoerper, KIF14 antikoerper, D1Ertd367e antikoerper, E130203M01 antikoerper, kinesin family member 14 antikoerper, kinesin-like protein KIF14 antikoerper, KIF14 antikoerper, kif14 antikoerper, LOC100641544 antikoerper, Kif14 antikoerper
    Hintergrund

    Background: Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:24784001, PubMed:16648480). During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively (PubMed:16431929). Regulates cell growth through regulation of cell cycle progression and cytokinesis (PubMed:24854087). During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resulting in positive regulation of cyclins, including CCNE1, CCND1 and CCNB1 (PubMed:24854087). During late neurogenesis, regulates the cerebellar, cerebral cortex and olfactory bulb development through regulation of apoptosis, cell proliferation and cell division (By similarity). Also is required for chromosome congression and alignment during mitotic cell cycle process (PubMed:15843429). Regulates cell spreading, focal adhesion dynamics, and cell migration through its interaction with RADIL resulting in regulation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtubules (PubMed:23209302).

    Aliases: KIAA0042 antibody, KIF 14 antibody, KIF14 antibody, KIF14_HUMAN antibody, Kinesin Family Member 14 antibody, Kinesin like protein KIF14 antibody, Kinesin-like protein KIF14 antibody, MGC142302 antibody

    UniProt
    Q15058
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