KIF2B Antikörper (AA 1607-1731)

Produktnummer ABIN7157616

Produktdetails anti-KIF2B Antikörper

Target: KIF2B (Kinesin Family Member 2B (KIF2B))

Bindungsspezifität: AA 1607-1731

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF2B Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Kinesin-like protein KIF20B protein (1607-1731AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu KIF2B

Target: KIF2B (Kinesin Family Member 2B (KIF2B))

Andere Bezeichnung: KIF2B (KIF2B Produkte)

Synonyme: 1700063D03Rik antikoerper, QtsA-13688 antikoerper, QtsA-18420 antikoerper, kinensin antikoerper, kinesin family member 2B antikoerper, Kif2b antikoerper, KIF2B antikoerper

Hintergrund:

Background: Plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth (By similarity). Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).

Aliases: Cancer/testis antigen 90 antibody, CT90 antibody, KI20B_HUMAN antibody, KIF20B antibody, Kinesin-like protein KIF20B antibody, Kinesin-related motor interacting with PIN1 antibody, KRMP1 antibody, M-phase phosphoprotein 1 antibody, MPHOSPH1 antibody, MPP 1 antibody, Mpp1 antibody

UniProt: Q96Q89

Pathways: Microtubule Dynamics