KMO Antikörper (AA 1-486)

Produktnummer ABIN7157756

Produktdetails anti-KMO Antikörper

Target: KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))

Bindungsspezifität: AA 1-486

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KMO Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Kynurenine 3-monooxygenase protein (1-486AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu KMO

Target: KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))

Andere Bezeichnung: KMO (KMO Produkte)

Synonyme: AI046660 antikoerper, dJ317G22.1 antikoerper, kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) antikoerper, kynurenine 3-monooxygenase antikoerper, Kmo antikoerper, KMO antikoerper

Hintergrund:

Background: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.

Aliases: dJ317G22.1 antibody, kmo antibody, KMO_HUMAN antibody, Kynurenine 3 hydroxylase antibody, Kynurenine 3 monooxygenase (kynurenine 3 hydroxylase) antibody, Kynurenine 3 monooxygenase antibody, Kynurenine 3-hydroxylase antibody, Kynurenine 3-monooxygenase antibody, RP1-317G22.1 antibody

UniProt: O15229