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KARS Antikörper (AA 101-400) (HRP)

KARS Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN7158686
  • Target Alle KARS Antikörper anzeigen
    KARS (Lysyl-tRNA Synthetase (KARS))
    Bindungsspezifität
    • 15
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 101-400
    Reaktivität
    • 51
    • 15
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 50
    • 2
    Kaninchen
    Klonalität
    • 42
    • 11
    Polyklonal
    Konjugat
    • 23
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KARS Antikörper ist konjugiert mit HRP
    Applikation
    • 34
    • 14
    • 13
    • 11
    • 10
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Lysine--tRNA ligase protein (101-400AA)
    Isotyp
    IgG
    Top Product
    Discover our top product KARS Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    KARS (Lysyl-tRNA Synthetase (KARS))
    Andere Bezeichnung
    KARS (KARS Produkte)
    Hintergrund

    Background: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA (PubMed:9278442, PubMed:18029264, PubMed:18272479). When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages (PubMed:15851690). Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity (PubMed:5338216, PubMed:14975237, PubMed:19524539, PubMed:23159739). (Microbial infection) Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA3(Lys), the primer for reverse transcription initiation.

    Aliases: CMTRIB antibody, DFNB89 antibody, EC 6.1.1.6 antibody, KARS 1 antibody, KARS 2 antibody, KARS antibody, KARS1 antibody, KARS2 antibody, KIAA0070 antibody, KRS antibody, Lysine tRNA ligase antibody, Lysine--tRNA ligase antibody, LysRS antibody, Lysyl tRNA synthetase antibody, Lysyl-tRNA synthetase antibody, SYK_HUMAN antibody

    UniProt
    Q15046
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