KDM2B Antikörper (AA 1274-1336) (Biotin)

Produktnummer ABIN7158692

Produktdetails anti-KDM2B Antikörper (Biotin)

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Bindungsspezifität: AA 1274-1336

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM2B Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Lysine-specific demethylase 2B protein (1274-1336AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu KDM2B

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Andere Bezeichnung: KDM2B (KDM2B Produkte)

Hintergrund:

Background: Histone demethylase that demethylates \'Lys-4\' and \'Lys-36\' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 \'Lys-4\' and dimethylated H3 \'Lys-36\' residue while it has weak or no activity for mono- and tri-methylated H3 \'Lys-36\'. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Aliases: [Histone-H3]-lysine-36 demethylase 1B antibody, CXXC-type zinc finger protein 2 antibody, CXXC2 antibody, F box and leucine rich repeat protein 10 antibody, F box protein FBL10 antibody, F-box and leucine-rich repeat protein 10 antibody, F-box protein FBL10 antibody, F-box/LRR-repeat protein 10 antibody, Fbl10 antibody, FBXL10 antibody, JEMMA (Jumonji domain EMSY interactor methyltransferase motif) protein antibody, JHDM1B antibody, JmjC domain-containing histone demethylation protein 1B antibody, Jumonji C domain containing histone demethylase 1B antibody, Jumonji domain-containing EMSY-interactor methyltransferase motif protein antibody, kdm2b antibody, KDM2B_HUMAN antibody, Lysine (K) specific demethylase 2B antibody, Lysine-specific demethylase 2B antibody, PCCX2 antibody, Protein containing CXXC domain 2 antibody, Protein JEMMA antibody, Protein-containing CXXC domain 2 antibody

UniProt: Q8NHM5

Pathways: Tube Formation, Warburg Effekt