KDM6A Antikörper (AA 620-749)

Produktnummer ABIN7158716

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KDM6A in ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für KDM6A Antikörper (AA 620-749) (ABIN7158716)

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM6A Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-KDM6A Antikörper

Bindungsspezifität: AA 620-749

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Lysine-specific demethylase 6A protein (620-749AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu KDM6A

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Andere Bezeichnung: KDM6A

Hintergrund:

Background: Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code (PubMed:17851529, PubMed:17713478, PubMed:17761849). Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27' (PubMed:17851529, PubMed:17713478, PubMed:17761849). Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529). Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (PubMed:17761849).

Aliases: bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX) antibody, bA386N14.2 antibody, bA386N14.2 ubiquitously transcribed X chromosome tetratricopeptide repeat protein UTX antibody, DKFZp686A03225 antibody, Histone demethylase UTX antibody, KABUK2 antibody, Kdm6a antibody, KDM6A_HUMAN antibody, Lysine (K) specific demethylase 6A antibody, Lysine K specific demethylase 6A antibody, Lysine specific demethylase 6A ubiquitously transcribed tetratricopeptide repeat gene X chromosome antibody, Lysine-specific demethylase 6A antibody, MGC141941 antibody, Ubiquitously transcribed tetratricopeptide repeat X chromosome antibody, Ubiquitously transcribed tetratricopeptide repeat protein X linked antibody, Ubiquitously transcribed TPR gene on the X chromosome antibody, Ubiquitously transcribed TPR protein on the X chromosome antibody, Ubiquitously transcribed X chromosome tetratricopeptide repeat protein antibody, Ubiquitously-transcribed TPR protein on the X chromosome antibody, Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein antibody, UTX antibody

UniProt: O15550

Pathways: Tube Formation, Warburg Effekt