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MST1R Antikörper (AA 1175-1400)

MST1R Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7158896
  • Target Alle MST1R Antikörper anzeigen
    MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
    Bindungsspezifität
    • 36
    • 19
    • 14
    • 12
    • 11
    • 11
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1175-1400
    Reaktivität
    • 89
    • 56
    • 36
    • 5
    • 1
    • 1
    • 1
    Human
    Wirt
    • 100
    • 3
    • 2
    Kaninchen
    Klonalität
    • 95
    • 10
    Polyklonal
    Konjugat
    • 35
    • 8
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser MST1R Antikörper ist unkonjugiert
    Applikation
    • 74
    • 32
    • 21
    • 19
    • 16
    • 15
    • 15
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Macrophage-stimulating protein receptor protein (1175-1400AA)
    Isotyp
    IgG
    Top Product
    Discover our top product MST1R Primärantikörper
  • Applikationshinweise
    Recommended dilution: IF:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
    Andere Bezeichnung
    MST1R (MST1R Produkte)
    Synonyme
    CD136 antikoerper, CDw136 antikoerper, PTK8 antikoerper, RON antikoerper, Fv-2 antikoerper, Fv2 antikoerper, Ron antikoerper, STK antikoerper, Cdw136 antikoerper, Ptk8 antikoerper, Stk antikoerper, macrophage stimulating 1 receptor antikoerper, macrophage stimulating 1 receptor (c-met-related tyrosine kinase) antikoerper, MST1R antikoerper, Mst1r antikoerper
    Hintergrund

    Background: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.

    Aliases: c met related tyrosine kinase antibody, CD136 antibody, CD136 antigen antibody, CDw136 antibody, Macrophage stimulating 1 receptor (c met related tyrosine kinase) antibody, Macrophage stimulating 1 receptor antibody, Macrophage stimulating protein receptor alpha chain antibody, MACROPHAGE STIMULATING PROTEIN RECEPTOR antibody, Macrophage stimulating protein receptor beta chain antibody, Macrophage-Stimulating 1 Receptor (MST1R) antibody, Macrophage-stimulating protein receptor beta chain antibody, MSP receptor antibody, Mst1r antibody, MST1R variant RON30 antibody, MST1R variant RON62 antibody, NPCA3 antibody, p185 RON antibody, p185-Ron antibody, Protein-tyrosine kinase 8 antibody, PTK 8 antibody, ptk8 antibody, PTK8 protein tyrosine kinase 8 antibody, Recepteur drigine nantais (RON) antibody, RON antibody, RON protein tyrosine kinase antibody, RON variant E2E3 antibody, RON_HUMAN antibody, Soluble RON variant 1 antibody, Soluble RON variant 2 antibody, Soluble RON variant 3 antibody, Soluble RON variant 4 antibody, Stem cell derived tyrosine kinase antibody

    UniProt
    Q04912
    Pathways
    RTK Signalweg
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