MR1 Antikörper (AA 150-253) (Biotin)

Produktnummer ABIN7158928

Produktdetails anti-MR1 Antikörper (Biotin)

Target: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Bindungsspezifität: AA 150-253

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MR1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Major histocompatibility complex class I-related gene protein (150-253AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MR1

Target: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Andere Bezeichnung: MR1 (MR1 Produkte)

Synonyme: YFV antikoerper, hlals antikoerper, MGC154362 antikoerper, MR1 antikoerper, DKFZp468C1823 antikoerper, HLALS antikoerper, H2ls antikoerper, Hlals antikoerper, MHC class I antigen YF5 antikoerper, major histocompatibility complex, class I-related antikoerper, major histocompatibility complex, class I-related L homeolog antikoerper, YF5 antikoerper, MR1 antikoerper, mr1.L antikoerper, mr1 antikoerper, Mr1 antikoerper

Hintergrund:

Background: Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.

Aliases: Class I histocompatibility antigen like protein antibody, Class I histocompatibility antigen-like protein antibody, HLALS antibody, HMR1_HUMAN antibody, Major histocompatibility complex class I like sequence antibody, Major histocompatibility complex class I related antibody, Major histocompatibility complex class I related gene protein antibody, Major histocompatibility complex class I related isoform CRA a antibody, Major histocompatibility complex class I related isoform CRA c antibody, Major histocompatibility complex class I related isoform CRA d antibody, Major histocompatibility complex class I-related gene protein antibody, MHC class I like antigen MR 1 antibody, MHC class I like antigen MR1 antibody, MHC class I related gene protein antibody, MHC class I related protein 1 isoform B antibody, MHC class I related protein 1 isoform C antibody, MHC class I-related gene protein antibody, MR 1 antibody, Mr1 antibody, Mr1 protein antibody, MR1B antibody, MR1C antibody

UniProt: Q95460

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints