MASP1 Antikörper (AA 20-699)
-
- Target Alle MASP1 Antikörper anzeigen
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
-
Bindungsspezifität
- AA 20-699
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser MASP1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Mannan-binding lectin serine protease 1 protein (20-699AA)
- Isotyp
- IgG
- Top Product
- Discover our top product MASP1 Primärantikörper
-
-
- Applikationshinweise
- Recommended dilution: WB:1:500-1:2000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
- Andere Bezeichnung
- MASP1 (MASP1 Produkte)
- Synonyme
- AW048060 antikoerper, CCPII antikoerper, Crarf antikoerper, Masp1/3 antikoerper, 3MC1 antikoerper, CRARF antikoerper, CRARF1 antikoerper, MAP1 antikoerper, MASP antikoerper, MASP3 antikoerper, MAp44 antikoerper, PRSS5 antikoerper, RaRF antikoerper, mannan-binding lectin serine peptidase 1 antikoerper, mannan binding lectin serine peptidase 1 antikoerper, Masp1 antikoerper, MASP1 antikoerper
- Hintergrund
-
Background: Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.
Aliases: MASP1 antibody, CRARF antibody, CRARF1 antibody, PRSS5Mannan-binding lectin serine protease 1 antibody, EC 3.4.21.- antibody, Complement factor MASP-3 antibody, Complement-activating component of Ra-reactive factor antibody, Mannose-binding lectin-associated serine protease 1 antibody, MASP-1 antibody, Mannose-binding protein-associated serine protease antibody, Ra-reactive factor serine protease p100 antibody, RaRF antibody, Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain, Mannan-binding lectin serine protease 1 light chain] antibody
- UniProt
- P48740
- Pathways
- Komplementsystem
-