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RIKEN cDNA 4930404A10 Gene (4930404A10RIK) (AA 18-91) Antikörper (FITC)

4930404A10RIK Reaktivität: Human Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN7159185
  • Target Alle RIKEN cDNA 4930404A10 Gene (4930404A10RIK) Antikörper anzeigen
    RIKEN cDNA 4930404A10 Gene (4930404A10RIK)
    Bindungsspezifität
    AA 18-91
    Reaktivität
    Human
    Wirt
    • 4
    Kaninchen
    Klonalität
    • 4
    Polyklonal
    Konjugat
    • 1
    • 1
    • 1
    • 1
    FITC
    Applikation
    Bitte anfragen
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Meiosis-specific kinetochore protein (18-91AA)
    Isotyp
    IgG
    Top Product
    Discover our top product 4930404A10RIK Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    RIKEN cDNA 4930404A10 Gene (4930404A10RIK)
    Andere Bezeichnung
    MEIKIN (4930404A10RIK Produkte)
    Synonyme
    4930404A10Rik antikoerper, meiotic kinetochore factor antikoerper, Meikin antikoerper
    Hintergrund

    Background: Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase-mediated cleavage. Acts by facilitating kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of the shugoshin-dependent protection pathway. Acts in collaboration with PLK1: required for PLK1 enrichment to kinetochores. Not required during meiosis II or mitosis.

    Aliases: MEIKINMeiosis-specific kinetochore protein antibody

    UniProt
    A0A087WXM9
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