SPO11 Antikörper (AA 28-109)

Produktnummer ABIN7159201

Produktdetails anti-SPO11 Antikörper

Target: SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))

Bindungsspezifität: AA 28-109

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPO11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Meiotic recombination protein SPO11 protein (28-109AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SPO11

Target: SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))

Andere Bezeichnung: SPO11 (SPO11 Produkte)

Synonyme: CT35 antikoerper, SPATA43 antikoerper, TOPVIA antikoerper, zgc:77876 antikoerper, AI449549 antikoerper, Meiotic recombination protein spo-11 antikoerper, SPO11, initiator of meiotic double stranded breaks antikoerper, SPO11 meiotic protein covalently bound to DSB antikoerper, spo-11 antikoerper, SPO11 antikoerper, Spo11 antikoerper, spo11 antikoerper

Hintergrund:

Background: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2.

Aliases: Cancer/testis antigen 35 antibody, CT35 antibody, Meiotic recombination protein SPO 11 antibody, Meiotic recombination protein SPO11 antibody, MGC39953 antibody, SPATA43 antibody, Spermatogenesis associated 43 antibody, SPO 11 antibody, SPO11 antibody, SPO11 meiotic protein covalently bound to DSB antibody, SPO11 meiotic protein covalently bound to DSB homolog antibody, SPO11 meiotic protein covalently bound to DSB like antibody, SPO11_HUMAN antibody, TOPVIA antibody

UniProt: Q9Y5K1