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KISS1 Antikörper (AA 20-138) (Biotin)

KISS1 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN7159563
  • Target Alle KISS1 Antikörper anzeigen
    KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
    Bindungsspezifität
    • 10
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-138
    Reaktivität
    • 47
    • 16
    • 4
    Human
    Wirt
    • 47
    • 4
    Kaninchen
    Klonalität
    • 48
    • 3
    Polyklonal
    Konjugat
    • 33
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KISS1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 23
    • 14
    • 13
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Metastasis-suppressor KiSS-1 protein (20-138AA)
    Isotyp
    IgG
    Top Product
    Discover our top product KISS1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
    Andere Bezeichnung
    KISS1 (KISS1 Produkte)
    Synonyme
    HH13 antikoerper, KiSS-1 antikoerper, metastatin antikoerper, Eseptin antikoerper, KiSS-1 metastasis-suppressor antikoerper, KISS1 antikoerper, kiss1 antikoerper, Kiss1 antikoerper
    Hintergrund

    Background: Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca(2+) levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine-tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.

    Aliases: KISS 1 antibody, KiSS 1 metastasis suppressor antibody, Kiss1 antibody, KISS1_HUMAN antibody, Kisspeptin 1 antibody, Kisspeptin 10 antibody, Kisspeptin 13 antibody, Kisspeptin 14 antibody, Kisspeptin antibody, Kisspeptin-1 antibody, Kisspeptin-10 antibody, Kisspeptin-54 antibody, Kisspeptin1 antibody, Malignant melanoma metastasis suppressor antibody, Metastasis suppressor KiSS 1 antibody, Metastasis suppressor KiSS1 antibody, Metastin antibody, MGC39258 antibody

    UniProt
    Q15726
    Pathways
    Positive Regulation of Peptide Hormone Secretion
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