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METRNL Antikörper (AA 46-311)

METRNL Reaktivität: Human ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7159569
  • Target Alle METRNL Antikörper anzeigen
    METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))
    Bindungsspezifität
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 46-311
    Reaktivität
    • 14
    • 13
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 22
    • 2
    Kaninchen
    Klonalität
    • 24
    Polyklonal
    Konjugat
    • 13
    • 5
    • 3
    • 3
    Dieser METRNL Antikörper ist unkonjugiert
    Applikation
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Meteorin-like protein (46-311AA)
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))
    Andere Bezeichnung
    METRNL (METRNL Produkte)
    Synonyme
    9430048M07Rik antikoerper, BC019776 antikoerper, fc90a08 antikoerper, fj23b04 antikoerper, wu:fc90a08 antikoerper, wu:fj23b04 antikoerper, zgc:56225 antikoerper, meteorin like, glial cell differentiation regulator antikoerper, meteorin, glial cell differentiation regulator-like antikoerper, meteorin-like, glial cell differentiation regulator antikoerper, meteorin, glial cell differentiation regulator-like L homeolog antikoerper, METRNL antikoerper, Metrnl antikoerper, metrnl.L antikoerper, metrnl antikoerper
    Hintergrund

    Background: Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures.

    Aliases: Meteorin like glial cell differentiation regulator antibody, Meteorin, glial cell differentiation regulator like antibody, Meteorin-like protein antibody, METRL_HUMAN antibody, Metrnl antibody

    UniProt
    Q641Q3
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