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MGMT Antikörper (AA 4-207)

MGMT Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7159622
  • Target Alle MGMT Antikörper anzeigen
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Bindungsspezifität
    • 17
    • 13
    • 11
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 4-207
    Reaktivität
    • 72
    • 19
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 68
    • 11
    Kaninchen
    Klonalität
    • 61
    • 18
    Polyklonal
    Konjugat
    • 44
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser MGMT Antikörper ist unkonjugiert
    Applikation
    • 55
    • 32
    • 21
    • 19
    • 13
    • 13
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Methylated-DNA--protein-cysteine methyltransferase protein (4-207AA)
    Isotyp
    IgG
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  • Applikationshinweise
    Recommended dilution: IHC:1:10-1:100,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Andere Bezeichnung
    MGMT (MGMT Produkte)
    Synonyme
    AGT antikoerper, AI267024 antikoerper, Agat antikoerper, O-6-methylguanine-DNA methyltransferase antikoerper, MGMT antikoerper, Mgmt antikoerper
    Hintergrund

    Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

    Aliases: 6 O methylguanine DNA methyltransferase antibody, 6-O-methylguanine-DNA methyltransferase antibody, Agat antibody, AGT antibody, AI267024 antibody, EC 2.1.1.63 antibody, Methylated DNA protein cysteine methyltransferase antibody, Methylated-DNA--protein-cysteine methyltransferase antibody, Methylguanine DNA methyltransferase antibody, MGC107020 antibody, MGMT antibody, MGMT_HUMAN antibody, O 6 methylguanine DNA alkyltransferase antibody, O 6 methylguanine DNA methyltransferase antibody, O-6-methylguanine-DNA methyltransferase antibody, O-6-methylguanine-DNA-alkyltransferase antibody

    UniProt
    P16455
    Pathways
    DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus
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