WDR77 Antikörper (AA 1-260)

Produktnummer ABIN7159661

Produktdetails anti-WDR77 Antikörper

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Bindungsspezifität: AA 1-260

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WDR77 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Methylosome protein 50 protein (1-260AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu WDR77

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Andere Bezeichnung: WDR77 (WDR77 Produkte)

Synonyme: MEP-50 antikoerper, MEP50 antikoerper, Nbla10071 antikoerper, RP11-552M11.3 antikoerper, p44 antikoerper, p44/Mep50 antikoerper, 2610003I18Rik antikoerper, 2610312E17Rik antikoerper, C79984 antikoerper, p44/MEP50 antikoerper, RGD1310479 antikoerper, mep50 antikoerper, valois antikoerper, WDR77 antikoerper, zgc:65780 antikoerper, zgc:77274 antikoerper, WD repeat domain 77 antikoerper, WD repeat domain 77 S homeolog antikoerper, WDR77 antikoerper, Wdr77 antikoerper, wdr77.S antikoerper, wdr77 antikoerper

Hintergrund:

Background: Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.

Aliases: 2610312E17Rik antibody, Androgen receptor cofactor p44 antibody, C79984 antibody, HKMT1069 antibody, MEP 50 antibody, MEP-50 antibody, MEP50 antibody, MEP50_HUMAN antibody, Methylosome protein 50 antibody, MGC2722 antibody, Nbla10071 antibody, p44 antibody, p44/Mep50 antibody, RGD1310479 antibody, RP11 552M11.3 antibody, WD repeat containing protein 77 antibody, WD repeat domain 77 antibody, WD repeat-containing protein 77 antibody, WDR77 antibody

UniProt: Q9BQA1

Pathways: Ribonucleoprotein Complex Subunit Organization