MCRS1 Antikörper (AA 1-138)

Produktnummer ABIN7159738

Produktdetails anti-MCRS1 Antikörper

Target: MCRS1 (Microspherule Protein 1 (MCRS1))

Bindungsspezifität: AA 1-138

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCRS1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Microspherule protein 1 protein (1-138AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MCRS1

Target: MCRS1 (Microspherule Protein 1 (MCRS1))

Andere Bezeichnung: MCRS1 (MCRS1 Produkte)

Hintergrund:

Background: Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus (PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity (PubMed:15044100). Binds to G-quadruplex structures in mRNA (PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U) (PubMed:16571602).

Aliases: 58 kDa microspherule protein antibody, Cell cycle regulated factor (78 kDa) antibody, Cell cycle regulated factor p78 antibody, Cell cycle-regulated factor p78 antibody, ICP22BP antibody, INO80 complex subunit J antibody, MCRS 1 antibody, MCRS 2 antibody, MCRS1 antibody, MCRS1_HUMAN antibody, MCRS2 antibody, Microspherule protein 1 antibody, MSP 58 antibody, MSP58 antibody, p78 antibody

UniProt: Q96EZ8