MACF1 Antikörper (AA 1936-2150)

Produktnummer ABIN7159742

Produktdetails anti-MACF1 Antikörper

Target: MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))

Bindungsspezifität: AA 1936-2150

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MACF1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 protein (1936-2150AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MACF1

Target: MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))

Andere Bezeichnung: MACF1 (MACF1 Produkte)

Synonyme: ABP620 antikoerper, ACF7 antikoerper, MACF antikoerper, OFC4 antikoerper, Acf7 antikoerper, Aclp7 antikoerper, R74989 antikoerper, mKIAA0465 antikoerper, MACF1 antikoerper, fc46g01 antikoerper, wu:fc46g01 antikoerper, si:rp71-45k5.7 antikoerper, acf7 antikoerper, macf antikoerper, ofc4 antikoerper, abp620 antikoerper, DKFZp469K2016 antikoerper, Kiaa0754 antikoerper, mKIAA0754 antikoerper, microtubule-actin crosslinking factor 1 antikoerper, microtubule-actin crosslinking factor 1a antikoerper, microtubule-actin cross-linking factor 1 antikoerper, dual specificity protein kinase CLK3 antikoerper, microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 antikoerper, KIAA0754 antikoerper, RIKEN cDNA D830031N03 gene antikoerper, MACF1 antikoerper, Macf1 antikoerper, macf1a antikoerper, macf1 antikoerper, LOC100175356 antikoerper, LOC100514848 antikoerper, LOC100550622 antikoerper, KIAA0754 antikoerper, D830031N03Rik antikoerper

Hintergrund:

Background: Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells (By similarity).

Aliases: MACF1 antibody, ABP620 antibody, ACF7 antibody, KIAA0465 antibody, KIAA1251 antibody, Microtubule-actin cross-linking factor 1 antibody, isoforms 1/2/3/5 antibody, 620 kDa actin-binding protein antibody, ABP620 antibody, Actin cross-linking family protein 7 antibody, Macrophin-1 antibody, Trabeculin-alpha antibody

UniProt: Q9UPN3